What is the working principle of the liquid-based thin-layer cytology system?

Release time:

2025-12-26 16:07

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The core working principle of the liquid-based thin-layer cytology system is to prepare high-quality cell smears through three steps: “sample processing—centrifugal separation—thin-layer smear preparation.”

Sample Preprocessing: Place the collected cell samples (such as cervical exfoliated cells or pleural/abdominal fluids) into containers containing a specialized preservation solution. This preservation solution stabilizes cell morphology, dissolves red blood cells and other impurities, and prevents cell degradation.
Centrifugal separation: Place the pre-processed sample into a centrifuge, where centrifugal force separates the target cells (such as diseased cells) from impurities like mucus and necrotic tissue, thereby enriching the desired cells.
Thin-layer preparation: The enriched cell suspension is evenly dropped onto a slide, dried, and stained to create a thin-layer cell smear. This ensures uniform cell distribution and intact cell morphology, facilitating observation and diagnosis by pathologists.

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